HPV cervical lesiond induced in the HIV positive woman

M. Mitran, C. Georgescu, S. Puia, M. Comanescu

Rezumat: The HPV-HIV co-infection represents an aggravating circumstance for the development of the cervical neoplasia. In the co-infection cases, the axiom according to which the HPV infection is asymptomatic and self-limited does not apply due to the immunological status of immunosuppression in the case of HIV positive patients. The study carried out over a period of 1 year confirms this hypothesis, namely: the HPV co-infection with clinical manifestation at the HIV positive patients is of 75%; the oncogene potential is much more increased than in the general population - 84.30%; the high-risk HPV roots are present in 67% of the cases. A diagnosis and a precocious therapeutic measure are required in this category of patients.
Cuvinte cheie: HIV, HPV, co-infection, oncogenesis.