Synchronous endometrial and ovarian carcinoma, endometrioid type – a pathologist’s insight. Case report

M. Olinca, A. Potecă, E. Brătilă, M. Mitran

Rezumat: Synchronous endometrial and ovarian carcinomas (SEOC) present a rare yet clinically significant occurrence, prompting challenges in diagnosis and management due to their heterogeneity in histological subtypes and molecular profiles. Diagnostic criteria, morphological features and the role of molecular analysis in differentiating between synchronous primaries and metastatic disease are discussed. Further investigation into predictive biomarkers and innovative therapies is crucial to enhance outcomes for these dual malignancies. The integration of molecular profiling, while promising, remains inconclusive in differentiating between independent primary tumors and metastatic disease, highlighting the need for further research and larger-scale studies in this field.
Cuvinte cheie: synchronous endometrial and ovarian carcinomas, SEOC, diagnosis, multidisciplinary approach, histological subtypes, morphological features.