Challenges and insights in managing systemic lupus erythematosus during pregnancy: a retrospective analysis of maternal and neonatal outcomes

A. Potorac, D. Vasilescu, A. Baroş, S. Vasilescu, A. Şerbănoiu, M.M. Cîrstoiu

Rezumat: Systemic lupus erythematosus (SLE), a chronic autoimmune disease predominantly affecting women during their reproductive years, presents unique challenges during pregnancy. This retrospective study, conducted at the Obstetrics and Gynecology Department of the Emergency University Hospital Bucharest, between 2021 and 2023, analyzes three cases of SLE in pregnancy to elucidate maternal and neonatal outcomes. Through the analysis of three compelling cases, the study navigates the complexities of severe preeclampsia, SLE flares, thrombocytopenia, intrauterine growth restriction and preterm delivery, each demanding a nuanced approach. The findings underscore the critical role of interdisciplinary collaboration and meticulous medication management, with a specific focus on the compatibility and efficacy of hydroxychloroquine. By unraveling the diverse clinical presentations and outcomes, the study contributes with valuable insights into optimizing pregnancy care for women grappling with systemic lupus erythematosus.
Cuvinte cheie: autoimmune disease, preeclampsia, thrombocytopenia, management.