E. Pop-Began, R. Vlădăreanu, S. Vlădăreanu, C. Pop-Began
Rezumat: From an immunological point of view, pregnancy is a
physiological condition treated by the body as a semiallograft,
the product of conception holding 50% of genetical
information from the partner. Hormonal and biochemical
changes specific to pregnancy lead to decreased immunity
in order to tolerate fetal development. This immune tolerance
causes an improvement in most autoimmune diseases
during pregnancy. However, there are some exceptions to
this rule, therefore in this article we present the case of a
pregnant woman who developed an exacerbation of the
clinical manifestations of pemphigus during pregnancy.
The informed consent was obtained from the patient for the
publication of this case. We chose to present this case due to
the rare incidence of pregnancy-associated pemphigus. Cuvinte cheie: pemphigus, pregnancy, autoimmune diseases, case report.