Thoracic surgery in lung metastases of genital cancers. Brief review of literature

I.M. Rădulescu, L. Rădulescu, M.M. Cîrstoiu, I. Cordoş

Rezumat: Malignant disease’s ability to metastasize remains one of the major obstacles when treating patients with cancer. The indication of metastasis resection is currently limited to patients undergoing treatment of the primary tumor. Resections for lung metastases of high selected patients with urogenital cancer present minimal risks and can prolong survival. Prognostic factors that determine which patients will benefit from surgery are still not clearly established. The criteria for surgery proven to have positive predictive value and that should be considered are: prolonged disease-free interval (DFI), unilateral disease, the absence of systemic pathologies, onchological margins rezecability and less than 3 radioimagistic detectable metastases. A negative prognosis was observed in those with primary tumor in the cervix, at least 3 metastasis and tumour larger than 3 cm. To determine how to select surgical candidates for pulmonary metastasectomy more precisely, further analysis of prognostic factors is evident and the need for a prospective, randomized, multicenter study is clear.
Cuvinte cheie: pulmonary metastases, urogenital cancer, pulmonary resection.