Inherited thrombophilia and placenta-mediated pregnancy complications

D. Voicu, O. Munteanu, L.V. Arsene, F. Păuleţ, O. Bodean, M. Cîrstoiu

Rezumat: Thrombophilia refers to a predisposition to hypercoagulable state and can be identified in 30-50% of the cases of venous thromboembolism. The etiology of thrombophilia is multifactorial and related to both acquired and inherited factors. In our study, 22.45% of the patients had a positive family history of venous thrombosis. Most of the patients had two (64.7%) or three (24%) spontaneous abortions, but cases of five or six recurrent miscarriages at the same patient were recorded in our study. Thrombophilia is diagnosed only by blood tests, and the current guidelines recommend that thrombophilia testing should be considered in case of recurrent miscarriages or fetal death.
Cuvinte cheie: thrombophilia, pregnancy, miscarriages.