Could bilateral salpingectomy reduce the risk of ovarian cancer?
N. Gică, R. Botezatu, G. Iancu, G. Peltecu, A.M. Panaitescu
Rezumat: Background. Epithelial ovarian cancer is the fifth
leading cause of cancer mortality among women.
There is no effective screening for ovarian cancer in the
current practice that could decrease its mortality. There
is a large volume of scientific proofs that prophylactic
salpingectomy could give the clinicians the opportunity
to prevent the development of ovarian cancer. The goal
of our paper is to sensitize the gynecologic community
and then to study in a prospective national trial the
potential use of prophylactic bilateral salpingectomy
as a primary preventive strategy of the ovarian cancer.
Objective. Currently, we have no prospective evidence
in order to analyze the effectiveness of prophylactic
bilateral salpingectomy in preventing ovarian cancer.
Through this article, we intend to launch an invitation to
all Romanian gynecologic surgery centers, to participate
in a prospective study evaluating the effectiveness of
bilateral salpingectomy in the prevention of ovarian
cancer. Materials and method. There is no strong
evidence regarding the effectiveness of bilateral
salpingectomy in the prevention of ovarian cancer and
this is the first multicenter, prospective trial in order
to study this hypothesis. Using this journal and other
media channels of the Romanian Society of Obstetrics
and Gynecology, we want to invite national centers
of obstetrics and gynecology to attend to our study.
All the centers need their ethical committee approval
before starting patients’ enrollment and a peculiar
informed consent adapted to this study. The deadline
for the approval is 1st of May 2018.The patients will
be consecutively selected from a general population
who undergo a surgical procedure during which the
fallopian tubes could be removed in addition to the
primary surgical procedure. All data needed regarding
the patient and the procedure will be collected in an
online document and kept into the database of the
department. The enrollment period will be from 1st
of June 2018 till May 30th 2021. Outcomes. Before
1st of August 2021 all the data must be collected and
prepared for publication. The effectiveness of bilateral
salpingectomy in the prevention of ovarian cancer
will be evaluated according to multiple variables. Cuvinte cheie: bilateral salpingectomy, ovarian cancer, ovarian cancer prevention.