REVISTA DE EDUCATIE MEDICALA CONTINUA DEDICATA GINECOLOGILOR,
OBSTETRICENILOR, MOASELOR SI ASISTENTILOR MEDICALI DIN ROMANIA

<- Home <- Arhive <- Anul 4, Nr. 12, June 2016



RevistaGinecologia4(12)18-22(2016)
© VERSA PULS MEDIA, S.R.L.


Pulmonary tuberculosis in pregnancy

A.P. Fildan, E. Brătilă, D. Tofolean, E. Danteş, S. Vlădăreanu


Rezumat: Tuberculosis (TB) remains an important cause of mortality and morbidity in pregnancy worldwide, being directly related to HIV epidemic. Immunological changes during pregnancy increase the risk of the latent TB infection reactivation or the potential of a new TB infection. Diagnosis of tuberculosis in pregnancy may be challenging, mainly because of the often nonspecific nature of the early symptoms of the disease, which may be attributed to pregnancy itself. TB treatment in pregnancy poses several problems, such as contraindications to anti-TB treatment, and their potential risks because of possible toxicity, changes in tolerability, pharmacokinetics of drugs, side effects, and the pill burden. There are no guidelines regarding the management of multidrugresistant (MDR) tuberculosis in pregnancy, the available data being provided only by case reports, and the second-line TB drugs, used for treating this form of TB, are known to be associated with obstetric, fetal, and infant complications. Improved diagnosis and treatment of TB in pregnant women are important interventions for both maternal and child health. Successful control of TB in pregnancy in high-prevalence areas demands a range of interventions, including BCG vaccination, active and latent TB screening in pregnant women, primary prevention of HIV-infected pregnant women, treatment of active and latent TB and public enlightenment.
Cuvinte cheie: pulmonary tuberculosis, pregnancy, anti-tuberculosis treatment.

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