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<- Home <- Arhive <- Anul 8, Nr. 29, Septembrie 2020



RevistaGinecologia8(29)8-12(2020)
© VERSA PULS MEDIA, S.R.L.


The management of a patient with pregnancy-acquired hemophilia – a case report

A.V. Uzunov, D. Secată, O. Munteanu, A.M. Oproiu, M.M. Cîrstoiu


Rezumat: Acquired hemophilia A (AHA) is a rare and severe hemorrhagic disorder in which the body produces specific antibodies against factor VIII of coagulation. AHA is an important coagulation disorder because it develops suddenly and it can be life-threatening due to fulminant bleeding. In women, AHA affects 20-30-year-olds, because of the relationship with pregnancy and puerperal period. Managing acquired hemophilia A during pregnancy or postpartum period can be a challenge, because the signs and symptoms can be confused with hemostasis disorders related to postpartum bleeding, such as coagulation factors deficiency, HELLP syndrome, Von Willebrand disease and others. Also, obstetrical causes for bleeding should be excluded, such as uterine atony, placental remnants or birth canal lesion. The treatment should be prompt and personalized according to each case, but the most important measures are to control the bleeding and to eradicate the inhibitors.
Cuvinte cheie: pregnancy, acquired hemophilia A, compartment syndrome.

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