REVISTA DE EDUCATIE MEDICALA CONTINUA DEDICATA GINECOLOGILOR,
OBSTETRICENILOR, MOASELOR SI ASISTENTILOR MEDICALI DIN ROMANIA

<- Home <- Arhive <- Anul 7, Nr. 24, Mai 2019



RevistaGinecologia7(24)30-33(2019)
© VERSA PULS MEDIA, S.R.L.


Association between preterm birth and genital colonization with Mycoplasma – literature review

A Rîcu, C Moisei, R Sima, C Bălălău, L Pleș


Rezumat: Preterm labor is responsible for most cases of neonatal death. In most of these cases, the causes have not been established, although several risk factors have been incriminated. Mycoplasma hominis is a common vaginal organism that is associated with bacterial vaginosis. The bacterium is considered inoffensive for the most part in nonpregnant women, but it can cause intraamniotic infections which are associated with inflammation, preterm premature rupture of membranes, and preterm birth. The role of these genital tract habitants in their infection during pregnancy and their capacity to invade placental and fetal tissue are discussed. In particular, the role of some of these organisms in prematurity may be mechanistically associated to their ability to induce inflammatory cytokines, thus triggering pathways causing to premature labor. A review of this intensifying research of mycoplasmas in relation to pregnancy lead to several questions and findings that will be important to examine in future research.
Cuvinte cheie: preterm birth, genital mycoplasmas, microbial invasion of the amniotic cavity.

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